The following are some of the technologies that have been invented by Eolas researchers:

The Cloud

Distributed hypermedia method for automatically invoking external application providing interaction and display of embedded objects within a hypermedia document

Inventors: Michael D. Doyle, David C. Martin and Cheong Ang

U.S. Patent 9,195,507, based on an application filed in October, 1994, Issued November 24, 2015 (the '507 Patent).

This powerful technology is widely used to deliver interactive content over the Web, transforming the Web into an application platform. A user's personal computer is able to tap into powerful remote computers without having to download large amounts of data to their local machine. The applications in part run remotely and the user interacts with the application data as if on their personal computer. Today, this powerful tool is popularly referred to as "The Cloud," and is used to deliver interactive content over the Web.

Many leading companies have licensed the invention, including Microsoft Corporation; Oracle Corporation; Adobe Systems Incorporated; Texas Instruments Incorporated; Office Depot, Inc.; CDW LLC; Staples, Inc.; eBay Inc.; JPMorgan Chase and Co.; Citigroup Inc.; The Go Daddy Group, Inc.; Argosy Publishing, Inc.; New Frontier Media, Inc.; Rent-A-Center, Inc.; and Frito-Lay, Inc.

The Eolas AnatLab System

The Eolas AnatLab System is a web-based virtual laboratory of human anatomical information which presents the user with a direct-manipulation interface to browse through a high-resolution reconstruction of an adult male cadaver. Users can slice the data from different directions, and interactively query a knowledge base by merely clicking on any structure in the section image. The AnatLab System responds by displaying the name of the anatomical structure and highlighting the extent of the structure on the section image being viewed. If the user clicks on the "more..." link, the system opens up a separate window and displays the corresponding Wikipedia page, to provide text-book style information and illustrations concerning the anatomical object of interest. The AnatLab product has been successfully beta-tested at the medical-school level.

A license for the AnatLab system has been donated by Eolas to the National Museum of Health + Medicine Chicago. The museum used the Eolas vScope cloud-based mobile virtual microscope subsystem of AnatLab to create the first neuroanatomical atlas of Albert Einstein's brain, released in 2012 as the Einstein Brain Atlas app in Apple's iPad app store, which received worldwide press coverage.

A demonstration video of an early version of the AnatLab system is available for viewing click here to download (76MB).

Transient-Key Cryptography

Method and system for transient key digital time stamps

Inventor: Michael D. Doyle

U.S. Patent 6,381,696, Filed Sept of 1998, Issued April 30, 2002

The Transient Key technology was inspired by the belief that real security can only be achieved by ensuring truth. If one can irrefutably and objectively prove that a piece of data existed at a point in time, and hasn't been changed since then, the truth represented by that data can be protected indefinitely. Now a part of the X.9.95 ANSI national standard for secure cryptographic timestamps, this invention uses concepts such as transient secret cryptographic keys and distributed cross-certification chains to provide a system for irrefutably certifying the time and state of any digital data, without the need for a third-party certificate authority. This technology has become especially important in light of legisltion passed by the U.S. Congress to tighten controls in the areas of information integrity assurance and data privacy protection. Dr. Doyle's Transient Key Time Stamp invention is a tool that enables compliance with regulations such as HIPAA and the Sarbanes-Oxley Act.

The SAGA System

Method and system for multidimensional morphological reconstruction of genome expression activity

Inventors: Michael D. Doyle, Betsey S.Williams, Maurice Pescitelli, George Michaels.

U.S. Patent 7,613,571, Filed July 27, 2001, Issued November 3, 2009

The SAGA system (Spatial Analysis of Genomic Activity) enables the automated large-scale discovery of the precise three-dimensional morphological distribution of the simultaneous gene expression activity of tens of thousands of genes in any biological tissue. The system combines the advantages of microarray chip technology with advanced 3-D visualization methods and advanced data analysis to provide a "snapshot" of the expression activity of all known genes within the spatial context of the biological structure.

zMap: Moving hotspots on video clips

Method and apparatus for identifying features of multidimensional image data in hypermedia systems

Inventor: Michael D. Doyle .

U.S. Patent 6,616,701, Filed on May 23, 1998, Issued September 9, 2003

This invention turns full-motion video into a fully-interactive experience. Imagine, for example, being able to view a movie trailer and being able to click on individual actors, as they move across the screen, to bring up Web pages with more information on their bios, other films, etc. Or imagine that you're watching a video of the 2015 NBA finals, and being able to click directly on any of the players at any time to retrieve their stats, where they are now, etc. The zMap technology makes all that possible, and more.

Browser API Simulation

Method and system for hypermedia browserAPI simulation to enable use of browser plug-ins and applets as embedded widgets in script-language-based interactive programs

Inventor: Michael D. Doyle.

U.S. Patent 6,857,124, Filed on Jan 11, 1999, Issued February 15, 2005

This invention provides the capability for high-level extensible scripting language interpreters to incorporate and employ Web browser plug-ins as components within script-based programs. A script interpreter extension is described which simulates the plug-in API interface of a Web browser, from the point of view of the browser plug-in, to allow program scripts to cause browser plug-ins to be launched and manipulated, in a manner similar to the scripting platform's native widgets, from within the executing program script. This system allows general program development systems to benefit from the large number of embeddable applications, in the form of browser plug-ins, that are available to easily expand the functionality of these development platforms at run-time, as well as to provide runtime binding of component logic with remotely-networked data object.

Widely witnessed proof of time

System and method for widely witnessed proof of time

Inventors: Michael D. Doyle, Paul F. Doyle, Glenn Bernsohn, Jeff Roberts, Kirk Wolf, and Stephen Goetze

U.S. Patent 7,047,415, Filed April 26, 2001, Issued May 16, 2006

A system for authenticating records without reliance upon a trusted third party. A first server provides a sequential series of certifications associated with discreet, non-overlapping time Intervals. The server can provide selected information to a second server which, in turn, incorporates the request and associated information in a cross-certification. The cross-certification is then provided to more other servers. Accordingly, a "chain-mail" of certifications among a variety of servers is provided. The system thus provides effective protection against a breach of security in any one server, resulting in increased reliability in the authentication of records.

Graphical indicia for the certification of records

System and method for graphical indicia for the certification of records

Inventors: Michael D. Doyle, Robert G. Hamilton, Marc V. Perrone, Paul F. Doyle, and Glenn Bernsohn

U.S. Patent 7,017,046, Filed April 26, 2001. Issued March 21, 2006

A system and method for authenticating records. Certification information may be encoded in graphical form. This graphical form, or design, may be referred to as an "Indicia." The record at issue may be printed out by a computer or stored electronically and bear on it an indicia that relates to the authenticity of the document. The indicia (and record) may then be scanned and interpreted by the computer to authenticate the record.

MetaMAP: The First Open-Linking Hypermedia System

Methods and apparatus for identifying features of an image on a video display
Inventor: Michael D. Doyle

U.S. Patent 4,847,604, Filed in August, 1987, Issued July 11, 1989

The MetaMAP system pioneered the use of clickable image maps in distributed hypermedia systems. It is also believed that the MetaMAP application was the first example of an “open-linking” hypermedia navigator, since it employed link references external to any single database. Previously, hypermedia systems were self-contained, representing all links between objects within a single monolithic database. A single small MetaMAP navigator application, on the other hand, could navigate through a potentially un-ending series of linked documents, no matter how large the collection of navigable documents might be. Later systems, such as the World Wide Web, similarly employed an open-linking architecture. The efficiencies that allowed the first MetaMAP application to provide instant object identification for tens of thousands of clickable objects in high resolution biomedical images, displayed on a 4.77MHz IBM PC,now enable the latest MetaMAP systems to deliver immensely-large multidimensionalnavigable image spaces for a variety of vertical applications.